Knowledge Base/Herbs/Dahurian Rhododendron Leaf
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化痰止咳平喘药(有小毒) · Phlegm-resolving, cough and breathing; classically toxic

Dahurian Rhododendron Leaf mǎn shān hóng · 满山红

Rhododendron dauricum L. (Rhododendri Daurici Folium)

Nature and flavour. Pungent and bitter, cold; Lung system.

Traditionally classed as stopping cough and dispelling phlegm, and recorded for cough with copious sputum and for congested breathing. It is a regional drug: the leaf of a rhododendron that grows across the north-east, used in the local and official materia medica rather than in the earliest classical canon, and it entered the modern Chinese pharmacopoeia as a leaf drug with an essential-oil fraction. The traditional picture is of a cold drug used for a hot, congested presentation, and it is classically paired with the warming cough drugs rather than substituted for them.

性味归经。辛、苦,寒;归肺经。

传统归类为止咳祛痰,古籍与地方本草用于痰多咳嗽、气喘。本品是地方性药品:为分布于东北的杜鹃属植物的叶,见于地方本草与现代药典,而非最早的经典本草;现代药典以叶入药,并记载其挥发油成分。传统认为本品性寒,用于属热、属壅滞之证,在配伍中与温性止咳药相须而用,不作简单替代。

Classical category · no formulas, no dosages, no herb-drug combinations are given.
Safety. The genus is the hazard. Rhododendron leaves contain grayanotoxin-type diterpenoids — andromedotoxin is one of them — and poisoning with this toxin class is well documented outside China as well, most famously as the illness caused by honey made from rhododendron nectar. The described course includes salivation, sweating, nausea and vomiting, dizziness and weakness, low blood pressure and a slow pulse, and in severe cases loss of consciousness; cardiac conduction effects and fits appear in the reports. Because the effect falls on blood pressure and heart rate, people with existing low blood pressure, with a slow pulse, or taking medicines that act on the heart or circulation are at greater risk. Species confusion is the other real problem: other rhododendrons are considerably more toxic — 羊踯躅 is classed as strongly toxic and has caused fatal poisoning — and a leaf gathered from the wrong shrub is not a weaker version of this drug but a different hazard. Forage-gathered or unlabelled leaf should not be used. Not for children. Safety in pregnancy and breastfeeding is not established; classically it is avoided in pregnancy.

危险来自这个属本身。杜鹃属叶含梫木毒素类二萜(梫木毒素即其中之一),此类毒素的中毒在中国之外亦有明确记载,最著名者为由杜鹃花蜜所致的中毒。文献描述的过程包括流涎、出汗、恶心呕吐、头晕乏力、血压下降与脉搏减慢,重症可致意识丧失;报告中亦有心脏传导影响与惊厥。因其作用落在血压与心率上,原有低血压、心动过缓,或正在服用作用于心脏与循环系统药物者风险更大。品种混淆是另一实际风险:杜鹃属其他种毒性明显更强 —— 羊踯躅被列为大毒并曾致死亡中毒 —— 采错灌木的叶不是本品的弱化版,而是另一种危险。自行采挖或无标签的叶不应使用。不用于儿童。孕期与哺乳期安全性未确立;传统列为孕妇忌用。

Other Phlegm-resolving, cough and breathing; classically toxic herbs

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