Knowledge Base/Formulas/Yin Chen Hao Tang
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清热利湿退黄;《伤寒论》治阳黄之祖方 · Clears heat, drains damp and reduces jaundice; the source formula for the pattern the literature calls yang jaundice

Yin Chen Hao Tang (Artemisia Capillaris Decoction) yīn chén hāo tāng · 茵陈蒿汤

Composition 组成

  • Virgate wormwood herb (yin chen hao)
  • gardenia fruit (zhi zi)
  • rhubarb root and rhizome (da huang).

组成

  • 茵陈蒿、栀子、大黄
Source 出处 · Shanghan Lun · Doses are not given here: they are set by a licensed practitioner for the individual.
Safety. Yin Chen Hao Tang is the reference formula for the picture the classical literature calls yang jaundice: yellowing that arrives with heat, a heavy and full body, bitter taste in the mouth, dark scanty urine, and a yellow greasy tongue coating. Three ingredients carry it. Yin chen hao drains damp; zhi zi clears the heat and, together with the rhubarb, pushes it downward; da huang opens the bowel so the heat has a way out. The design is transparent, and this entry will not pretend it is not. The problem is not the design. The problem is the presenting sign. Jaundice is not a disease. It is a finding, and the list behind it is long: viral hepatitis A through E, alcoholic and autoimmune hepatitis, drug-induced liver injury - herbal preparations included - gallstone disease, obstruction of the bile duct by stone or by tumour, pancreatic head cancer, haemolysis, congestive hepatopathy from heart failure, and Gilbert syndrome, which needs no treatment at all. Several of these are urgent or surgical. Obstructive jaundice and acute cholangitis, the second announced by fever and rigors alongside the pain, belong to endoscopy and surgery rather than to a decoction. In a newborn, jaundice is a separate problem again with a separate time course, and kernicterus is the reason it is assessed urgently rather than managed at home. Modern medicine has also changed what jaundice means. Chronic hepatitis B is now managed with antivirals and chronic hepatitis C is cured in most people by direct-acting antiviral drugs; neither achievement has an herbal equivalent, and no formula in this library should be read as a substitute for a causal treatment. Yin chen hao is a genuine diuretic and choleretic herb with a long clinical record in China and, as inchinkoto, a place in the Japanese Kampo formulary as a prescription pharmaceutical preparation. What the classical sources promise - that the yellow recedes - is a traditional outcome description, and the controlled evidence for meaningful clinical endpoints is not something this entry can assert. Practical cautions follow from the ingredients. Rhubarb contains anthraquinones and is a stimulant laxative: it should not be used in suspected bowel obstruction or an undiagnosed acute abdomen, and long-term use is associated with electrolyte disturbance and dependence. Gardenia fruit has been reported to cause liver injury in preclinical studies and in case reports, which is an uncomfortable fit for a formula given for jaundice, and it is why this entry records the signal rather than smoothing it away. Yin chen hao is an Artemisia, and Artemisia pollen is one of the more common aeroallergens; the species used also varies by pharmacopoeia and region, so the plant named in a text is not always the plant in the packet. Pregnancy and breastfeeding are reasons not to take a formula built partly on a stimulant laxative.

茵陈蒿汤是古典文献所说「阳黄」的标准方:身黄而伴热象、身重腹满、口苦、小便短赤、舌苔黄腻。三味各司其职:茵陈蒿利湿,栀子清热并与大黄同引热下行,大黄通腑使热有出路。这个方义是清楚的,本条目不去掩饰它。 问题不在方义,而在它所对的那个症状。黄疸不是一种病,而是一个体征,它背后的清单很长:甲至戊型病毒性肝炎、酒精性与自身免疫性肝炎、药物性肝损伤(草本制剂也在其列)、胆石症、结石或肿瘤造成的胆道梗阻、胰头癌、溶血、心衰导致的充血性肝病,以及完全不需要处理的 Gilbert 综合征。其中若干项属于急症或外科范畴。梗阻性黄疸与急性胆管炎(后者以腹痛伴寒战高热为标志)属于内镜与外科处理,不属于汤药。新生儿黄疸则完全是另一条时间线,胆红素脑病是它必须被紧急评估而不是居家处置的理由。 现代医学也已经改变了黄疸的含义:慢性乙型肝炎已由抗病毒药物控制病程,慢性丙型肝炎在大多数人身上可被直接抗病毒药物清除。这两项成就没有草药对应物,本库任何方剂都不应被读作对因治疗的替代品。茵陈蒿确有真实的利胆与利尿记载,在日本汉方体系中,同名方(茵蔯蒿湯)作为医疗用汉方制剂被使用。古典文献所承诺的「黄退」是传统疗效描述,而达到有意义临床终点的对照证据,本条目不作断言。 具体注意事项来自三味药本身。大黄含蒽醌,属刺激性泻药:疑似肠梗阻或未判明的急腹症不宜使用,长期服用与电解质紊乱及依赖性相关。栀子在临床前研究与病例报告中均有肝损伤记载,这对一首用于黄疸的方而言是个令人不安的巧合,本条目因此把这个信号记下来而不是抹平它。茵陈蒿是蒿属植物,而蒿属花粉是常见的气传过敏原之一;所用物种又随药典与地区而变,故书里写的植物与包里的植物并不总是一回事。孕期与哺乳期不适合服用部分由刺激性泻药构成的方剂。

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